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Targeted Allele Detail
Symbol: Grm6tm1Nak
Name: glutamate receptor, metabotropic 6; targeted mutation 1, Shigetada Nakanishi
MGI ID: MGI:1857985
Synonyms: mGluR6-
Gene: Grm6  Location: Chr11:50741512-50757035 bp, + strand  Genetic Position: Chr11, 30.93 cM
Germline Transmission:  Earliest citation of germline transmission: J:48532
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced 1.2 kb of sequence encoding part of the transmembrane region. Northern blot analysis did not detect transcript in retina from homozygous mutant mice. (J:48532)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Grm6 Mutation:  40 strains or lines available
Original:  J:48532 Masu M, et al., Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell. 1995 Mar 10;80(5):757-65
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory