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Prrx2tm1Mjk
Targeted Allele Detail
Summary
Symbol: Prrx2tm1Mjk
Name: paired related homeobox 2; targeted mutation 1, Michael J Kern
MGI ID: MGI:1857684
Synonyms: Prx2-
Gene: Prrx2  Location: Chr2:30735076-30771263 bp, + strand  Genetic Position: Chr2, 21.74 cM
Alliance: Prrx2tm1Mjk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52212
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe third exon, which encodes the DNA binding domain, was deleted. Molecular details were not included in the original reference. (J:51596)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 36 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prrx2 Mutation:  11 strains or lines available
References
Original:  J:52212 Lu MF, et al., Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Dev Biol. 1999 Jan 1;205(1):145-57
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory