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Targeted Allele Detail
Symbol: Wnt5atm1Amc
Name: wingless-type MMTV integration site family, member 5A; targeted mutation 1, Andrew P McMahon
MGI ID: MGI:1857617
Synonyms: Wnt5a-
Gene: Wnt5a  Location: Chr14:28226707-28249405 bp, + strand  Genetic Position: Chr14, 16.8 cM
Primordial germ cell depletion in Ror2Y324C/Ror2Y324C and Wnt5atm1Amc/Wnt5atm1Amc mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:52600
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 2 was disrupted at codon 31 by the insertion of a neomycin selection cassette. (J:52600)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 229 assay results
In Structures Affected by this Mutation: 33 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt5a Mutation:  28 strains or lines available
Original:  J:52600 Yamaguchi TP, et al., A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development. 1999 Mar;126(6):1211-23
All:  98 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory