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Wnt5atm1Amc
Targeted Allele Detail
Nomenclature
Symbol: Wnt5atm1Amc
Name: wingless-type MMTV integration site family, member 5A; targeted mutation 1, Andrew P McMahon
MGI ID: MGI:1857617
Synonyms: Wnt5a-
Gene: Wnt5a  Location: Chr14:28504750-28527447 bp, + strand  Genetic Position: Chr14, 16.8 cM
Primordial germ cell depletion in Ror2Y324C/Ror2Y324C and Wnt5atm1Amc/Wnt5atm1Amc mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52600
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 2 was disrupted at codon 31 by the insertion of a neomycin selection cassette. (J:52600)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 112 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt5a Mutation:  8 strains or lines available
References
Original:  J:52600 Yamaguchi TP, et al., A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development. 1999 Mar;126(6):1211-23
All:  65 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory