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Atp2b2dfw-2J
Spontaneous Allele Detail
Nomenclature
Symbol: Atp2b2dfw-2J
Name: ATPase, Ca++ transporting, plasma membrane 2; deaf waddler 2 Jackson
MGI ID: MGI:1857396
Synonyms: dfw-2J
Gene: Atp2b2  Location: Chr6:113720792-114019574 bp, - strand  Genetic Position: Chr6, 52.85 cM
Mutation
origin
Strain of Origin:  CByJ.A-Ttc7fsn/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsA 2 bp nucleotide deletion at positions 1368 and 1369 cause a frameshift that results in a premature stop and truncation of the encoded protein at position 471. (J:48969)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atp2b2 Mutation:  53 strains or lines available
References
Original:  J:38429 Noben-Trauth K, et al., mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw). Genomics. 1997 Sep 15;44(3):266-72
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory