About   Help   FAQ
Cybbtm1Din
Targeted Allele Detail
Nomenclature
Symbol: Cybbtm1Din
Name: cytochrome b-245, beta polypeptide; targeted mutation 1, Mary C Dinauer
MGI ID: MGI:1857284
Synonyms: Cybb KO, Cybbtm1, Cybbtm1Din, gp91-, gp91phox, gp91phox-, gp91phox-, Nox-2-, NOX2-, PHOX-, X-CGD
Gene: Cybb  Location: ChrX:9435252-9487771 bp, - strand  Genetic Position: ChrX, 4.3 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:22868
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cybb Mutation:  2 strains or lines available
References
Original:  J:22868 Pollock JD, et al., Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nat Genet. 1995 Feb;9(2):202-9
All:  288 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/16/2014
MGI 5.19
The Jackson Laboratory