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Rab38cht
Spontaneous Allele Detail
Nomenclature
Symbol: Rab38cht
Name: RAB38, member RAS oncogene family; chocolate
MGI ID: MGI:1856819
Synonyms: chocolate, cht
Gene: Rab38  Location: Chr7:88079481-88140780 bp, + strand  Genetic Position: Chr7, 49.19 cM
Brown coat color in Rab38cht/Rab38cht mice (right)

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA G-to-T transversion mutation at coding nucleotide 56 (c.56G>T) in exon 1 results in a glycine to valine substitution in codon 19 of the gene (p.G19V). This mutation lies within the highly conserved phosphate/Mg2+ domain. (J:75774)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rab38 Mutation:  11 strains or lines available
Notes
This allele has been maintained on the C57BL/6J background at The Jackson Laboratory since 1984 when it was first identified.
References
Original:  J:13967 MacPike A, et al., New coat color mutations, Dbr and cht. Mouse News Lett. 1984;70:86
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory