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Spontaneous Allele Detail
Symbol: Ay
Name: nonagouti; agouti yellow
MGI ID: MGI:1856798
Synonyms: Ay, A(y)
Gene: a  Location: Chr2:154950599-155051012 bp, + strand  Genetic Position: Chr2, 76.83 cM
Ay/a mouse

Show the 4 phenotype image(s) involving this allele.

Strain of Origin:  old mutant of the mouse fancy
Allele Type:    Spontaneous
Mutation:    Other
Mutation detailsThe Ay mutation appears to be a DNA structural alteration that disrupts a gene, hnRNP associated with lethal yellow (Raly), 5' to the agouti locus and places the agouti locus under the control of the Raly promotor. A report of recombination between Ay and the a and ax alleles suggests that Ay was a pseudoallele of the a locus on the proximal side. However, cloning of the agouti locus and molecular analysis of a showed that the coding region of the three alleles is identical. (J:8877, J:12911, J:17512, J:18921)
Inheritance:    Semidominant
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 15 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 11 strains available      Cell Lines: 0 lines available
Carrying any a Mutation:  478 strains or lines available
Original:  J:12954 Dunn LC, et al., Studies on Spotting Patterns III. Interaction between Genes Affecting White Spotting and Those Affecting Color in the House Mouse. Genetics. 1937 Mar;22(2):307-18
All:  179 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory