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Cdh23v-bus
Spontaneous Allele Detail
Nomenclature
Symbol: Cdh23v-bus
Name: cadherin 23 (otocadherin); bustling waltzer
MGI ID: MGI:1856681
Synonyms: BUS/Idr
Gene: Cdh23  Location: Chr10:60302748-60696490 bp, - strand  Genetic Position: Chr10, 30.11 cM
Mutation
origin
Strain of Origin:  KYF/MsIdr
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdh23 Mutation:  58 strains or lines available
Notes
Cdh23, bustling, recessive. An inbred strain bearing Jsr at the Institute for Developmental Research in Japan produced offspring expressing a hyperkinetic behavior pattern. When crossed to the KYF/MsIdr inbred strain, the abnormality did not appear in the F1 generation, but reappeared in 21% of F2 mice and 44% of mice from a backcross to bustling forebears. These proportions were not significantly different from those expected for a recessive autosomal trait. Hyperkinetic females reproduce well, but it is difficult for them to care for neonatal offspring (J:12975).

References
Original:  J:12975 Shoji R, Congenital hyperkinesia. Mouse News Lett. 1988;81:68
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory