Lbr^ic-4J
Spontaneous Allele Detail

Summary

• Symbol: Lbr^ic-4J
• Name: lamin B receptor; ichthyosis 4 Jackson
• MGI ID: MGI:1856507
• Synonyms: ic^4J
• Gene: Lbr Location: Chr1:181642880-181669966 bp, - strand Genetic Position: Chr1, 84.89 cM
• Alliance: Lbr^ic-4J page

Mutation origin

• Strain of Origin: C3H/HeJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This phenotypic mutant was found to be allelic to ic by complementation testing. The mutation in the ic^4J mouse was identified as 4 bp insertion at position 1815. This insertion results in a frame shift changing amino acids (606-627) and adds 21 amino acids to the carboxy end of the protein.
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbr Mutation: 55 strains or lines available

Notes

Mouse line is extinct but DNA may be available.

References

• Original: J:30778 Sweet HO, et al., Remutations at The Jackson Laboratory (Update to Mouse Genome 1993; 91:862-5 - J16313). Mouse Genome. 1995;93(4):1030-4
• All: 1 reference(s)