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Gdf5bp-3J
Spontaneous Allele Detail
Nomenclature
Symbol: Gdf5bp-3J
Name: growth differentiation factor 5; brachypodism 3 Jackson
MGI ID: MGI:1856340
Gene: Gdf5  Location: Chr2:155941023-155945367 bp, - strand  Genetic Position: Chr2, 77.26 cM
Mutation
origin
Strain of Origin:  BALB/cJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsA CG dinucleotide was replaced by a single base pair (T) at position 876, causing a frame shift and a translational stop at the next codon. (J:17582)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gdf5 Mutation:  20 strains or lines available
Notes
The long bones of the limbs of mutant mice are slightly shorter than controls, and the fibula is shortened proximally. The bones of the axial skeleton are unaffected.
References
Original:  J:16313 Sweet HO, Remutations at The Jackson Laboratory. Mouse Genome. 1993;91(4):862-65
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory