Fgf5^go
Spontaneous Allele Detail

Summary

• Symbol: Fgf5^go
• Name: fibroblast growth factor 5; angora
• MGI ID: MGI:1856336
• Synonyms: FGF-5-, go
• Gene: Fgf5 Location: Chr5:98402108-98424892 bp, + strand Genetic Position: Chr5, 47.77 cM, cytoband E1-F
• Alliance: Fgf5^go page

Mutation origin

• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: Sequences encoding exon 1 are deleted in this mutation. The deletion extends at least 2 kb 5' to the translation start site. Expression of Fgf5 in hair follicles of wild-type mice is localized to the outer root sheath during the hair production phase of the follicle cycle. FGF5 may function as an inhibitor of hair elongation. (J:20551)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Fgf5 Mutation: 14 strains or lines available

References

• Original: J:13413 Dickie MM, Angora. Mouse News Lett. 1963;29:39
• All: 10 reference(s)