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Pax6Sey-Dey
Spontaneous Allele Detail
Summary
Symbol: Pax6Sey-Dey
Name: paired box 6; small eye, Dickie
MGI ID: MGI:1856157
Synonyms: SeyDey
Gene: Pax6  Location: Chr2:105499245-105527709 bp, + strand  Genetic Position: Chr2, 55.31 cM
Alliance: Pax6Sey-Dey page
The Pax6Sey-Dey/Pax6+ mouse

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C3H/HeJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intergenic deletion
 
Mutation detailsA large deletion that also includes the neighboring Wilm's tumor gene (Wt1). Precise breakpoints have not been mapped. (J:10820)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 17 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Pax6Sey-Dey
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax6 Mutation:  90 strains or lines available
Notes
Pax6Sey-Dey is very similar to Pax6Sey-H in its effects in both homozygotes and heterozygotes.
References
Original:  J:24775 Varnum D, et al., Dickie's small eye (Dey). Mouse News Lett. 1974;50:43
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory