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Pax6Sey
Spontaneous Allele Detail
Summary
Symbol: Pax6Sey
Name: paired box 6; small eye
MGI ID: MGI:1856155
Synonyms: P5, Pax6-, Pax6SeyEd, sey
Gene: Pax6  Location: Chr2:105499245-105527709 bp, + strand  Genetic Position: Chr2, 55.31 cM
Alliance: Pax6Sey page
Development of the Pax6Sey/Pax6+ lens

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  Line selected for low body weight
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA G-to-T transversion in coding nucleotide 622 (NM_001244198.2) changes the glycine codon at position 208 to a stop codon (Gly208*; NP_001231127.1), resulting in premature termination before the homeobox domain. (J:2301)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 788 assay results
3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 36 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 9 strains available      Cell Lines: 0 lines available
Carrying any Pax6 Mutation:  90 strains or lines available
References
Original:  J:12101 Roberts RC, Small-eyes, a new dominant mutant in the mouse. Genet Res. 1967;9(1):121-122
All:  174 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory