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MitfMi-wh
Spontaneous Allele Detail
Nomenclature
Symbol: MitfMi-wh
Name: microphthalmia-associated transcription factor; white
MGI ID: MGI:1856088
Synonyms: mitfwh, Miwh
Gene: Mitf  Location: Chr6:97807058-98021349 bp, + strand  Genetic Position: Chr6, 45.05 cM
MitfMi-wh/+ and MitfMi-wh/MitfMi-wh and control

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  (C57BL x DBA)F1
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation details
Inheritance:    Semidominant
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 8 strains available      Cell Lines: 0 lines available
Carrying any Mitf Mutation:  41 strains or lines available
Notes
Combination heterozygotes of MitfMi-wh/MitfMi, MitfMi-wh/MitfMi-b, and MitfMi-wh/MitfMi-ws show some interallelic complementation in that the heterozygote of the two alleles is more nearly normal than either homozygote (J:12967, J:19656). MitfMi-b/MitfMi-wh agouti mice are light cream with white spots and ruby eyes (J:15061).

References
Original:  J:13058 Grobman AB, et al., Mutant white mice. A new dominant autosomal mutant affecting coat color in Mus musculus. J Hered. 1947;38:381-384
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory