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Myo5ad-l
Spontaneous Allele Detail
Summary
Symbol: Myo5ad-l
Name: myosin VA; dilute lethal
MGI ID: MGI:1856005
Synonyms: dl
Gene: Myo5a  Location: Chr9:74978297-75130970 bp, + strand  Genetic Position: Chr9, 42.26 cM
Alliance: Myo5ad-l page
Mutation
origin
Strain of Origin:  C57BL/Gr
Mutation
description
Allele Type:    Spontaneous
Mutation:    Undefined
    This Myo5a allele was identifed by a noncomlementation test result with Myo5ad. (J:12978)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Myo5a Mutation:  231 strains or lines available
Notes
Myo5ad-l, dilute-lethal, recessive. Dilute-lethal arose in the C57BL/Gr strain. The color of Myo5ad-l homozygotes is identical to that of Myo5ad homozygotes, but dilute-lethal mice develop a severe neuromuscular disorder characterized by convulsions and opisthotonus (arching upward of the head and tail), and they usually die at about 3 weeks of age (J:12978).
References
Original:  J:24768 Searle AG, New mutant, allele of Maltese dilution, d. Mouse News Lett. 1951;4:10
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory