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Aiy
Spontaneous Allele Detail
Nomenclature
Symbol: Aiy
Name: nonagouti; intermediate yellow
MGI ID: MGI:1855933
Gene: a  Location: Chr2:154791402-155051012 bp, + strand  Genetic Position: Chr2, 76.83 cM
Mutation
origin
Strain of Origin:  C3H/HeJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Transposon insertion
 
Mutation detailsThis allele is the result of a 1 kb intracisternal A particle (IAP) transposon insertion. Genomic Southern hybridization analysis places the insertion just upstream of exon 2. (J:19977)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any a Mutation:  449 strains or lines available
Notes
The Avy allele arose spontaneously in the C3H/HeJ strain. Heterozygotes (Aiy/a) are sootier than Ay/a and are often indistinguishable from A/a. They do not have the mottling often observed in Avy/a. Homozygotes are viable, as are Avy/Ay and Aiy/Avy (J:13441).

Genbank ID for this mutation: S74469

References
Original:  J:13441 Dickie MM, Intermediate yellow. Mouse News Lett. 1966;34:30
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/09/2018
MGI 6.12
The Jackson Laboratory