Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mapk14tm1.1Lex
Name:	mitogen-activated protein kinase 14; targeted mutation 1.1, Lexicon Genetics
MGI ID:	MGI:5548094
Synonyms:	p38alphadelta
Gene:	Mapk14  Location: Chr17:28910303-28967380 bp, + strand  Genetic Position: Chr17, 14.85 cM
Alliance:	Mapk14tm1.1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:119724
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: LoxP sites were inserted to flank the first exon, which contains the ATG. Cre-mediated recombination removed the first exon. (J:119724)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk14 Mutation:	41 strains or lines available

Original:	J:119724 Perdiguero E, et al., Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J. 2007 Mar 7;26(5):1245-56
All:	1 reference(s)