Phenotypes associated with this allele

• Allele Symbol: Mapk14^tm1.1Lex
• Allele Name: targeted mutation 1.1, Lexicon Genetics
• Allele ID: MGI:5548094
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mapk14^tm1.1Lex/Mapk14^tm1.1Lex	involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J	MGI:5548097

Genotype
MGI:5548097

hm1

• Allelic Composition: Mapk14^tm1.1Lex/Mapk14^tm1.1Lex
• Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal myoblast differentiation ( J:119724 )

• impaired as determined by marker expression

• impaired myoblast fusion and cell cycle-exit

abnormal myoblast fusion ( J:119724 )

• impaired myoblast fusion

increased myoblast proliferation ( J:119724 )

• mice exhibit increased myoblast proliferation in the neonatal period compared with control mice

abnormal muscle fiber morphology ( J:119724 )

• exhibit delayed myofiber growth and maturation in the neonatal period compared with control mice

cellular

abnormal myoblast differentiation ( J:119724 )

• impaired as determined by marker expression

• impaired myoblast fusion and cell cycle-exit

abnormal myoblast fusion ( J:119724 )

• impaired myoblast fusion

increased myoblast proliferation ( J:119724 )

• mice exhibit increased myoblast proliferation in the neonatal period compared with control mice