Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Marcotm1Spt
Name:	macrophage receptor with collagenous structure; targeted mutation 1, Shari Pilon-Thomas
MGI ID:	MGI:5538543
Gene:	Marco  Location: Chr1:120402267-120432753 bp, - strand  Genetic Position: Chr1, 52.71 cM, cytoband E4-F
Alliance:	Marcotm1Spt page

Germline Transmission:	Earliest citation of germline transmission: J:204315
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exons 16 and 17. Immunohistochemistry confirmed the absence of protein expression in dendritic cells. (J:204315)

Generation of the Marcotm1Spt allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Marco Mutation:	34 strains or lines available

Original:	J:204315 Komine H, et al., Examination of MARCO activity on dendritic cell phenotype and function using a gene knockout mouse. PLoS One. 2013;8(7):e67795
All:	1 reference(s)