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Fetubtm1Wja
Targeted Allele Detail
Summary
Symbol: Fetubtm1Wja
Name: fetuin beta; targeted mutation 1, Willi Jahnen-Dechent
MGI ID: MGI:5514274
Gene: Fetub  Location: Chr16:22737132-22758518 bp, + strand  Genetic Position: Chr16, 13.76 cM, cytoband B
Alliance: Fetubtm1Wja page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196435
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  (129/Sv x C57BL/6)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in sera. (J:196435)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fetub Mutation:  38 strains or lines available
Notes
ES cell line = Knut 1
References
Original:  J:196435 Dietzel E, et al., Fetuin-B, a liver-derived plasma protein is essential for fertilization. Dev Cell. 2013 Apr 15;25(1):106-12
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory