Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Azgp1tm1.1Sbah
Name:	alpha-2-glycoprotein 1, zinc; targeted mutation 1.1, Seiamak Bahram
MGI ID:	MGI:5431920
Synonyms:	ZAP-
Gene:	Azgp1  Location: Chr5:137979783-137988495 bp, + strand  Genetic Position: Chr5, 76.92 cM
Alliance:	Azgp1tm1.1Sbah page

Germline Transmission:	Earliest citation of germline transmission: J:118213
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons alpha 1 and 2 were replaced with a floxed neo cassette. Cre mediated recombination removed the neo cassette. Western blot analysis confirmed the absence of protein expression in liver, kidney, fat depots, serum, heart, lung, stomach, intestine, spleen, brain and testis. (J:118213)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Azgp1 Mutation:	15 strains or lines available

Original:	J:118213 Rolli V, et al., Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice. FEBS Lett. 2007 Feb 6;581(3):394-400
All:	1 reference(s)