All Phenotypes Azgp1<tm1.1Sbah> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Azgp1^tm1.1Sbah
targeted mutation 1.1, Seiamak Bahram
MGI:5431920

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Azgp1^tm1.1Sbah/Azgp1^tm1.1Sbah	involves: 129P2/OlaHsd * C57BL/6	MGI:5431925

Allelic Composition	Azgp1^tm1.1Sbah/Azgp1^tm1.1Sbah
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Azgp1^tm1.1Sbah mutation (1 available); any Azgp1 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:118213 )

• when fed standard food or a high fat diet

enlarged spleen ( J:118213 )

• in mice fed a high fat diet

adipose tissue

• adipocytes stimulated with forskolin, IBMX, isoprenaline or CL316243 exhibit impaired lipolysis compared with wild-type cells

homeostasis/metabolism

impaired lipolysis ( J:118213 )

• in adipocytes stimulated with forskolin, IBMX, isoprenaline or CL316243

hematopoietic system

enlarged spleen ( J:118213 )

• in mice fed a high fat diet

immune system

enlarged spleen ( J:118213 )

• in mice fed a high fat diet

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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