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Tsc22d3tm1.1Ric
Targeted Allele Detail
Summary
Symbol: Tsc22d3tm1.1Ric
Name: TSC22 domain family, member 3; targeted mutation 1.1, Carlo Riccardi
MGI ID: MGI:5308358
Synonyms: Gilz KO
Gene: Tsc22d3  Location: ChrX:139440277-139501257 bp, - strand  Genetic Position: ChrX, 61.35 cM, cytoband F1
Alliance: Tsc22d3tm1.1Ric page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:179667
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsOne loxP site was inserted upstream of exon 6 and a second loxP was placed downstream. An FRT flanked neomycin cassette was located further downstream. Exon 6 was then excised in properly targeted mice. (J:179667)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tsc22d3 Mutation:  5 strains or lines available
References
Original:  J:179667 Bruscoli S, et al., Long Glucocorticoid-induced Leucine Zipper (L-GILZ) Protein Interacts with Ras Protein Pathway and Contributes to Spermatogenesis Control. J Biol Chem. 2012 Jan 6;287(2):1242-51
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory