Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Crptm1Hjf
Name:	C-reactive protein, pentraxin-related; targeted mutation 1, H J Fehling
MGI ID:	MGI:4947397
Gene:	Crp  Location: Chr1:172525623-172527533 bp, + strand  Genetic Position: Chr1, 80.13 cM
Alliance:	Crptm1Hjf page

Germline Transmission:	Earliest citation of germline transmission: J:170409
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced coding sequence in exon 1 and most of exon 2. The absence of protein expression was confirmed by western blot anaylsis on serum. (J:170409)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crp Mutation:	16 strains or lines available

Original:	J:170409 Teupser D, et al., No reduction of atherosclerosis in C-reactive protein (CRP)-deficient mice. J Biol Chem. 2011 Feb 25;286(8):6272-9
All:	2 reference(s)