Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Csgalnact1tm1.1Nari
Name:	chondroitin sulfate N-acetylgalactosaminyltransferase 1; targeted mutation 1.1, Hisashi Narimatsu
MGI ID:	MGI:4947395
Gene:	Csgalnact1  Location: Chr8:68809433-69187798 bp, - strand  Genetic Position: Chr8, 33.88 cM
Alliance:	Csgalnact1tm1.1Nari page

Germline Transmission:	Earliest citation of germline transmission: J:170410
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. The absence of transcript expression was confirmed by real time PCR on brain extracts. (J:170410)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	96 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csgalnact1 Mutation:	33 strains or lines available

Original:	J:170410 Sato T, et al., Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism. J Biol Chem. 2011 Feb 18;286(7):5803-12
All:	2 reference(s)