Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd44tm2.1Ugu
Name:	CD44 antigen; targeted mutation 2.1, Ursula Gunthert
MGI ID:	MGI:4835490
Synonyms:	CD44v10-/-, CD44v10-/-
Gene:	Cd44  Location: Chr2:102641486-102732010 bp, - strand  Genetic Position: Chr2, 54.13 cM
Alliance:	Cd44tm2.1Ugu page

Germline Transmission:	Earliest citation of germline transmission: J:82809
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele was generated from Cd44tm2Ugu by Cre recombinase excision of the neomycin resistance cassette and exon 10. (J:199279)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Cd44 Mutation:	67 strains or lines available

Original:	J:199279 Ghazi-Visser L, et al., CD44 variant isoforms control experimental autoimmune encephalomyelitis by affecting the lifespan of the pathogenic T cells. FASEB J. 2013 Sep;27(9):3683-701
All:	3 reference(s)