Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trip10tm1.1Geha
Name:	thyroid hormone receptor interactor 10; targeted mutation 1.1, Raif S Geha
MGI ID:	MGI:4834223
Gene:	Trip10  Location: Chr17:57556455-57570665 bp, + strand  Genetic Position: Chr17, 29.74 cM
Alliance:	Trip10tm1.1Geha page

Germline Transmission:	Earliest citation of germline transmission: J:164363
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Exons 4 through 11 were replaced with an FRT flanked neo cassette. Flp mediated recombination removed the neo cassette. The absence of protein expression was confirmed by western blot analysis of lung extract. (J:164363)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trip10 Mutation:	31 strains or lines available

Original:	J:164363 Koduru S, et al., Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16252-6
All:	1 reference(s)