Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tbpl2tm1.1Lzt
Name:	TATA box binding protein like 2; targeted mutation 1.1, Laszlo Tora
MGI ID:	MGI:4360523
Synonyms:	Tbp2-
Gene:	Tbpl2  Location: Chr2:23961733-23986607 bp, - strand  Genetic Position: Chr2, 16.14 cM
Alliance:	Tbpl2tm1.1Lzt page

Germline Transmission:	Earliest citation of germline transmission: J:152449
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination removed exon 4. The absence of protein expression was confirmed by western blot analysis on ovary extracts. (J:152449)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbpl2 Mutation:	30 strains or lines available

Original:	J:152449 Gazdag E, et al., TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte. Genes Dev. 2009 Sep 15;23(18):2210-23
All:	3 reference(s)