Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rtel1tm1.1Hdin
Name:	regulator of telomere elongation helicase 1; targeted mutation 1.1, Hao Ding
MGI ID:	MGI:3772371
Synonyms:	Rteldeltaexon7
Gene:	Rtel1  Location: Chr2:180961532-180998409 bp, + strand  Genetic Position: Chr2, 103.63 cM
Alliance:	Rtel1tm1.1Hdin page

Germline Transmission:	Earliest citation of germline transmission: J:130490
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 7 was removed by germ-line, cre-mediated recombination. Deletion of exon 7 results in a frame shift and premature termination of the peptide. The presence of only the truncated form of the transcript was confirmed by RT-PCR analysis. (J:130490)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rtel1 Mutation:	73 strains or lines available

Original:	J:130490 Wu X, et al., Establishment of conditional knockout alleles for the gene encoding the regulator of telomere length (RTEL). Genesis. 2007 Dec;45(12):788-92
All:	1 reference(s)