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Pdcd1lg2tm2Shr
Targeted Allele Detail
Summary
Symbol: Pdcd1lg2tm2Shr
Name: programmed cell death 1 ligand 2; targeted mutation 2, Arlene H Sharpe
MGI ID: MGI:3720327
Synonyms: PD-L2-
Gene: Pdcd1lg2  Location: Chr19:29388319-29448561 bp, + strand  Genetic Position: Chr19, 23.93 cM, cytoband C2-C3
Alliance: Pdcd1lg2tm2Shr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123785
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A targeting vector replaced the IgV exon with a hygromycin resistance gene. (J:123785)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdcd1lg2 Mutation:  23 strains or lines available
References
Original:  J:123785 Keir ME, et al., Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med. 2006 Apr 17;203(4):883-95
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory