Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd40tm1Arah
Name:	CD40 antigen; targeted mutation 1, Amin Rahemtulla
MGI ID:	MGI:3707600
Synonyms:	CD40-
Gene:	Cd40  Location: Chr2:164897535-164913574 bp, + strand  Genetic Position: Chr2, 85.38 cM
Alliance:	Cd40tm1Arah page

Germline Transmission:	Earliest citation of germline transmission: J:120512
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S1/Sv

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin resistance cassette was inserted into exon 3. (J:120512)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd40 Mutation:	48 strains or lines available

Original:	J:120512 Ensminger SM, et al., Critical role for IL-4 in the development of transplant arteriosclerosis in the absence of CD40-CD154 costimulation. J Immunol. 2001 Jul 1;167(1):532-41
All:	1 reference(s)