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Rettm1.1Kln
Targeted Allele Detail
Summary
Symbol: Rettm1.1Kln
Name: ret proto-oncogene; targeted mutation 1.1, Rudiger Klein
MGI ID: MGI:3662902
Synonyms: Ret-, Ret-null
Gene: Ret  Location: Chr6:118128706-118174679 bp, - strand  Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
Alliance: Rettm1.1Kln page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110955
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsMice carrying the Rettm1Kln floxed allele were crossed to Deleter-Cre mice (Tg(Pgk1-cre)1Lni) to excise the floxed region and to generate heterozygous mice. (J:110955)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ret Mutation:  53 strains or lines available
References
Original:  J:110955 Kramer ER, et al., Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron. 2006 Apr 6;50(1):35-47
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory