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Gadd45gtm1Mhol
Targeted Allele Detail
Summary
Symbol: Gadd45gtm1Mhol
Name: growth arrest and DNA-damage-inducible 45 gamma; targeted mutation 1, M Christine Hollander
MGI ID: MGI:3653832
Gene: Gadd45g  Location: Chr13:52000714-52002504 bp, + strand  Genetic Position: Chr13, 26.36 cM, cytoband A5-B
Alliance: Gadd45gtm1Mhol page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110650
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A fragment of Gadd45g including exons 1-3 was replaced with a PMG-neo cassette. (J:199917)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gadd45g Mutation:  8 strains or lines available
References
Original:  J:110650 Cai Q, et al., Effects of expression of p53 and Gadd45 on osmotic tolerance of renal inner medullary cells. Am J Physiol Renal Physiol. 2006 Aug;291(2):F341-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory