Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Afdntm1Ytk
Name:	afadin, adherens junction formation factor; targeted mutation 1, Yoshimi Takai
MGI ID:	MGI:3623108
Synonyms:	afadin-
Gene:	Afdn  Location: Chr17:13980735-14126059 bp, + strand  Genetic Position: Chr17, 8.95 cM, cytoband A2
Alliance:	Afdntm1Ytk page

Germline Transmission:	Earliest citation of germline transmission: J:57589
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin resistance gene replaced exon 2. (J:57589)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Afdn Mutation:	84 strains or lines available

Original:	J:57589 Ikeda W, et al., Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol. 1999 Sep 6;146(5):1117-32
All:	1 reference(s)