Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnab1tm1Kwak
Name:	potassium voltage-gated channel, shaker-related subfamily, beta member 1; targeted mutation 1, Seung P Kwak
MGI ID:	MGI:3621902
Synonyms:	Kvbeta1-
Gene:	Kcnab1  Location: Chr3:64856636-65285643 bp, + strand  Genetic Position: Chr3, 30.15 cM
Alliance:	Kcnab1tm1Kwak page

Germline Transmission:	Earliest citation of germline transmission: J:106860
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1.1, which encodes the first 36 amino acids of the locus, was replaced by three copies of the HA epitope tag. A neomycin resistance cassette, flanked by loxP sites, was inserted into intron 1.1. (J:106860)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnab1 Mutation:	27 strains or lines available

Original:	J:106860 Aimond F, et al., Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes. Circ Res. 2005 Mar 4;96(4):451-8
All:	1 reference(s)