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Steap3tm1.1Mdf
Targeted Allele Detail
Summary
Symbol: Steap3tm1.1Mdf
Name: STEAP family member 3; targeted mutation 1.1, Mark D Fleming
MGI ID: MGI:3609928
Gene: Steap3  Location: Chr1:120154137-120198810 bp, - strand  Genetic Position: Chr1, 52.66 cM, cytoband E2
Alliance: Steap3tm1.1Mdf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:103440
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsPart of intron 1, all of exon 2 and part of intron 2 have been deleted. A single loxP sequence marks the site where the remaining 5' segment of intron 1 and the 3' segment of intron 2 are joined. (J:103440)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Steap3 Mutation:  63 strains or lines available
References
Original:  J:103440 Ohgami RS, et al., Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet. 2005 Nov;37(11):1264-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory