Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pdzk1tm1Dls
Name:	PDZ domain containing 1; targeted mutation 1, David L Silver
MGI ID:	MGI:3588076
Synonyms:	PDZK1-
Gene:	Pdzk1  Location: Chr3:96736772-96778242 bp, + strand  Genetic Position: Chr3, 42.0 cM
Alliance:	Pdzk1tm1Dls page

Germline Transmission:	Earliest citation of germline transmission: J:100280
Parent Cell Line:	CSL3 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1, containing the ATG, and part of intron 1 were replaced by neomycin resistance cassette. Western blot of mutant liver lysates confirmed absence of protein. (J:100280)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdzk1 Mutation:	25 strains or lines available

Original:	J:100280 Lan D, et al., Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1. J Biol Chem. 2005 Jun 17;280(24):23390-6
All:	7 reference(s)