Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hexim1tm1Maqs
Name:	hexamethylene bis-acetamide inducible 1; targeted mutation 1, M A Q Siddiqui
MGI ID:	MGI:3052225
Synonyms:	CLP-1-, Cpl1tm1Maqs
Gene:	Hexim1  Location: Chr11:103007151-103010551 bp, + strand  Genetic Position: Chr11, 66.71 cM
Alliance:	Hexim1tm1Maqs page

Germline Transmission:	Earliest citation of germline transmission: J:92209
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced the coding exon. Northern blot of livers indicated lack of transcript in mutant mice. (J:92209)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	47 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hexim1 Mutation:	10 strains or lines available

Original:	J:92209 Huang F, et al., Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72
All:	9 reference(s)