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Epha3tm1Abn
Targeted Allele Detail
Summary
Symbol: Epha3tm1Abn
Name: Eph receptor A3; targeted mutation 1, Arthur Brown
MGI ID: MGI:2681606
Synonyms: Efna3tm1Abn, EphA3-
Gene: Epha3  Location: Chr16:63363897-63684538 bp, - strand  Genetic Position: Chr16, 36.49 cM
Alliance: Epha3tm1Abn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86478
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced by a neomycin resistance gene. Western blot analysis on E12.5 spinal cord protein extracts demonstrated the absence of gene product. (J:86478)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 14 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Epha3 Mutation:  80 strains or lines available
References
Original:  J:86478 Vaidya A, et al., EphA3 null mutants do not demonstrate motor axon guidance defects. Mol Cell Biol. 2003 Nov;23(22):8092-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory