Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgfr1tm1.1Jpa
Name:	fibroblast growth factor receptor 1; targeted mutation 1.1, Juha Partanen
MGI ID:	MGI:2657013
Synonyms:	Fgfr1deltaflox
Gene:	Fgfr1  Location: Chr8:26008808-26067819 bp, + strand  Genetic Position: Chr8, 14.12 cM
Alliance:	Fgfr1tm1.1Jpa page

Germline Transmission:	Earliest citation of germline transmission: J:83004
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed region encompassing exons 8 through 15 was excised via cre-mediated recombination in the germline. (J:83004)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:	221 strains or lines available

Original:	J:83004 Trokovic R, et al., FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15;22(8):1811-23
All:	9 reference(s)