Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr27tm1.1Kpfe
Name:	regulatory region 27; targeted mutation 1.1, Karl Pfeifer
MGI ID:	MGI:2655219
Synonyms:	DMRDeltaG, H19tm1.1Kpfe
Gene:	Rr27  Location: unknown  Genetic Position: Chr7, Syntenic
Alliance:	Rr27tm1.1Kpfe page

Germline Transmission:	Earliest citation of germline transmission: J:82798
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The floxed 0.1 kb region containing the differentially methylated region (DMR) was excised from Rr27tm1Kpfe via cre-mediated recombination in the germ line. (J:82798)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr27 Mutation:	6 strains or lines available

Original:	J:82798 Srivastava M, et al., H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19. Genes Dev. 2000 May 15;14(10):1186-95
All:	3 reference(s)