Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kat2btm1Roth
Name:	K(lysine) acetyltransferase 2B; targeted mutation 1, Sharon Y Roth
MGI ID:	MGI:2386280
Synonyms:	Pcaf-
Gene:	Kat2b  Location: Chr17:53873889-53979748 bp, + strand  Genetic Position: Chr17, 27.86 cM
Alliance:	Kat2btm1Roth page

Germline Transmission:	Earliest citation of germline transmission: J:65002
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The exon 376 bp downstream of the translational start site was replaced by a cassette containing a polyA signal followed by a PGK-neo. An absence of transcript in homozygous mutant mice was determined by Northern blot analysis of a variety of tissues. (J:65002)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kat2b Mutation:	152 strains or lines available

Original:	J:65002 Xu W, et al., Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32
All:	5 reference(s)