Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ltb4r1tm1Bodd
Name:	leukotriene B4 receptor 1; targeted mutation 1, Bodduluri Haribabu
MGI ID:	MGI:2385781
Synonyms:	BLTR-, BTL1-
Gene:	Ltb4r1  Location: Chr14:56003419-56005951 bp, + strand  Genetic Position: Chr14, 28.19 cM
Alliance:	Ltb4r1tm1Bodd page

Germline Transmission:	Earliest citation of germline transmission: J:63874
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: 706 bp of the coding region was replaced with a PGK-neo cassette via homologous recombination resulting in the deletion of amino acids 81-316 from the encoded protein. Homozygous mutant animals were identified by PCR genotype analysis and Southern blot. (J:63874)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ltb4r1 Mutation:	20 strains or lines available

Original:	J:63874 Haribabu B, et al., Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis [see comments]. J Exp Med. 2000 Aug 7;192(3):433-8
All:	14 reference(s)