Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Syptm1Sud
Name:	synaptophysin; targeted mutation 1, Thomas C Sudhof
MGI ID:	MGI:2179741
Synonyms:	syp I deficient
Gene:	Syp  Location: ChrX:7504819-7519495 bp, + strand  Genetic Position: ChrX, 3.44 cM, cytoband A-D
Alliance:	Syptm1Sud page

Germline Transmission:	Earliest citation of germline transmission: J:33035
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exon 3 and flanking sequences. Western blot analysis on brain lysates from homozygous mice confirmed that no detectable encoded protein was present. (J:33035)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Syp Mutation:	22 strains or lines available

Original:	J:33035 McMahon HT, et al., Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4760-4
All:	4 reference(s)