About   Help   FAQ
Cebpetm1Kgx
Targeted Allele Detail
Summary
Symbol: Cebpetm1Kgx
Name: CCAAT/enhancer binding protein epsilon; targeted mutation 1, Kleanthis G Xanthopoulos
MGI ID: MGI:2178607
Synonyms: C/EBPepsilon-
Gene: Cebpe  Location: Chr14:54947823-54949604 bp, - strand  Genetic Position: Chr14, 27.9 cM
Alliance: Cebpetm1Kgx page
Cebpetm1Kgx/Cebpetm1Kgx mice exhibit a variety of lesions associated with opportunistic bacetrial infections

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76024
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.2 kb genomic fragment containing 334 bp of sequence encoding the bZIP region was replaced with a neomycin selection cassette. Northern blot analysis on RNA derived from bone marrow cells demonstrated that no detectable transcript was expressed from this allele. (J:76024)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cebpe Mutation:  12 strains or lines available
References
Original:  J:76024 Yamanaka R, et al., Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13187-92
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory