Rr27tm1Msb
Targeted Allele Detail
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| Symbol: |
Rr27tm1Msb |
| Name: |
regulatory region 27; targeted mutation 1, Marisa S Bartolomei |
| MGI ID: |
MGI:1930792 |
| Synonyms: |
H19deltaDMDneo, H19tm1Msb |
| Gene: |
Rr27 Location: unknown Genetic Position: Chr7, Syntenic
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| Alliance: |
Rr27tm1Msb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:52162
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| Parent Cell Line: |
E14.1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP-flanked neomycin resistance gene cassette replaced the region of the gene from approximately -2 to -4kb relative to the H19 transcription start site (the DMD domain).
(J:52162)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rr27 Mutation: |
6 strains or lines available
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| Original: |
J:52162 Thorvaldsen JL, et al., Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev. 1998 Dec 1;12(23):3693-702 |
| All: |
1 reference(s) |
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Analysis Tools
