Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grm6tm1Nak
Name:	glutamate receptor, metabotropic 6; targeted mutation 1, Shigetada Nakanishi
MGI ID:	MGI:1857985
Synonyms:	mGluR6-
Gene:	Grm6  Location: Chr11:50741512-50757035 bp, + strand  Genetic Position: Chr11, 30.93 cM
Alliance:	Grm6tm1Nak page

Germline Transmission:	Earliest citation of germline transmission: J:48532
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced 1.2 kb of sequence encoding part of the transmembrane region. Northern blot analysis did not detect transcript in retina from homozygous mutant mice. (J:48532)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Grm6 Mutation:	51 strains or lines available

Original:	J:48532 Masu M, et al., Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell. 1995 Mar 10;80(5):757-65
All:	21 reference(s)