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Gene Expression Data
Assay Details
Assay
Reference: J:98919 Cobb J, et al., Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development. 2005 Jul;132(13):3055-67
Assay type: RNA in situ
MGI Accession ID: MGI:3689899
Gene symbol: Papss2
Gene name: 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Probe: Papss2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S2A Wild type E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present S2A Wild type E11.5

Specimen S2A HoxD Del1-13 E11.5: embryonic day 11.5; Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present S2A HoxD Del1-13 E11.5 Expression was detected as in wild type.

Specimen S2A Wild type E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit Present S2A Wild type E12.5

Specimen S2A HoxD Del1-13 E12.5: embryonic day 12.5; Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu (more )
Structure Level Pattern Image Note
TS20: forelimb digit Weak S2A HoxD Del1-13 E12.5 Expression was markedly reduced in mutant limbs.

Specimen S2A Wild type E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb digit Present S2A Wild type E13.5

Specimen S2A HoxD Del1-13 E13.5: embryonic day 13.5; Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu (more )
Structure Level Pattern Image Note
TS21: forelimb digit Weak S2A HoxD Del1-13 E13.5

Specimen S2A Wild type E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb digit Weak S2A Wild type E14.5 Expression in wild type digits decreased from E12.5.

Specimen S2A HoxD Del1-13 E14.5: embryonic day 14.5; Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu (more )
Structure Level Pattern Image Note
TS22: forelimb digit Weak S2A HoxD Del1-13 E14.5 Due to the decrease in wild type expression at this stage, expression in mutant is higher than in wild type.

Specimen S2C Wild type E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: genital tubercle Trace S2C Wild type

Specimen S2C HoxD Del1-13 E14.5: embryonic day 14.5; Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu (more )
Structure Level Pattern Image Note
TS22: genital tubercle Trace S2C HoxD Del1-13


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory