Gene Expression Data
Assay Details
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Assay
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Reference:
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J:47700
Greene ND, et al., Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects. Mech Dev. 1998 Apr;73(1):59-72
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3529945
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Gene symbol:
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T
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Gene name:
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brachyury, T-box transcription factor T
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Probe:
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T cDNA9
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Probe preparation:
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Antisense RNA
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Results
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Specimen
4A +/+:
embryonic day 8.5
(more  )
Specimen
4A +/+:
(close  )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4A Lp/+:
embryonic day 8.5; Vangl2Lp/Vangl2 +
(more )
Specimen
4A Lp/+:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Mutant Allele(s):
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Vangl2Lp/Vangl2+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4A Lp/Lp:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Mutant Allele(s):
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Vangl2Lp/Vangl2Lp
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4B +/+:
embryonic day 9.5
(more )
Specimen
4B +/+:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Age:
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embryonic day 9.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4B Lp/+:
embryonic day 9.5; Vangl2Lp/Vangl2 +
(more )
Specimen
4B Lp/+:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Mutant Allele(s):
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Vangl2Lp/Vangl2+
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Age:
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embryonic day 9.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: notochord |
Present |
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4B Lp/+
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Heterozygotes exhibit an intermediate level of expression compared to wild type and homozygotes.
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Specimen
4B Lp/Lp:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Mutant Allele(s):
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Vangl2Lp/Vangl2Lp
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: notochord |
Present |
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4B Lp/Lp
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Homozygotes exhibit an increased level of expression compared to wild type.
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Specimen
4C:
embryonic day 9.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Specimen
4D:
(close )
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Genetic Background:
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involves: CBA/Ca * LPT/Le
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Mutant Allele(s):
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Vangl2Lp/Vangl2Lp
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: notochord |
Present |
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4D
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The notochord is broader in the homozygote compared to wild type.
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Analysis Tools