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Gene Expression Data
Assay Details
Assay
Reference: J:79514 Burke Z, et al., Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev. 2002 Oct;118(1-2):147
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3529572
Gene symbol: Prox1
Gene name: prospero homeobox 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 7.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS11: node Present 1A

Specimen 1C: embryonic day 8.0; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 6-8 somites.
Structure Level Pattern Image Note
TS12: primitive streak Present Regionally restricted 1C Expression is present in the regressing node.

Specimen 1D: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 8-10 somites.
Structure Level Pattern Image Note
TS13: primitive streak Present Regionally restricted 1D Expression is present in the regressing node.

Specimen 1E: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 10-12 somites.
Structure Level Pattern Image Note
TS13: foregut-midgut junction endoderm Present Regionally restricted 1E Expression is present in the hepatic endoderm.
TS13: primitive streak Present Regionally restricted 1E Expression is present in the regressing node.

Specimen 1F: embryonic day 9.0; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 15-18 somites.
Structure Level Pattern Image Note
TS14: hepatic primordium Present 1F Expression is present in the liver bud.
TS14: foregut-midgut junction Present Regionally restricted 1F Expression is present in the dorsal pancreas.
TS14: hindgut diverticulum Present Regionally restricted 1F Expression is present in the hindgut near the region of the node.

Specimen 2A: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS13: foregut-midgut junction endoderm Present Regionally restricted 2A Expression is present in the hepatic endodoerm.
TS13: primitive streak Present Regionally restricted 2A Expression is present in the regressing node.
TS13: notochord Present Regionally restricted 2A Expression is present in the notochord in the area around the regressing node.
TS13: hindgut diverticulum Present 2A Expression is present in the hindgut.

Specimen 3A: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS13: foregut-midgut junction endoderm Present Regionally restricted 3A Expression is present in the hepatic endoderm.

Specimen 5A: embryonic day 9.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS14: foregut-midgut junction Strong Regionally restricted 5A Expression is present in the hepatic bud and the dorsal and ventral pancreatic buds.
TS14: tail bud Present Regionally restricted 5A Expression is present in the posterior node in the tail bud region.
TS14: hindgut diverticulum Present 5A

Specimen 6A: embryonic day 9.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS15: hepatic primordium Strong 6A Expression is present in the hepatic bud and the ventral and dorsal pancreatic buds.
TS15: pancreas primordium Strong 6A Expression is present in the hepatic bud and the ventral and dorsal pancreatic buds.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory